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GIP receptor engagement adds metabolic sensitivity: cells respond more acutely to insulin signaling, which improves glucose handling and accelerates fat mobilization
The timeline is straightforward but its implications are anything but simple
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(2017) 152:313321.e2
For now, clinicians should document MASH with fibrosis stage clearly, reference the new indication verbatim, and include persuasive language when requesting approval (e.g., FDA approval does not require obesity
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